Dr. Gregory Haljan is leading a clinical trial of a COVID-19 antibody. (Contributed photo)

Dr. Gregory Haljan is leading a clinical trial of a COVID-19 antibody. (Contributed photo)

B.C.-based clinical trial of COVID-19 antibody ‘very promising,’ says expert

Participation criteria expanded for infusion clinic based at Peace Arch Hospital

The clinical trial of a drug that one expert says looks “very promising” for use in stopping the progression of COVID-19 moved into a new phase this week, with the opportunity to participate now open to all eligible patients in the Fraser Health region.

Dr. Gregory Haljan – head of Surrey Memorial Hospital’s critical care unit and Fraser Health’s regional medical director for research – said Monday (April 26) that around 300 COVID-19-positive patients are sought to receive the medication bamlanivimab as part of the B-EPIC (Bamlanivimab-Emergency Passive Immunity in COVID-19) study.

READ MORE: Clinical trial of COVID-19 drug for severe cases to be carried out at Surrey hospital

Designed in January, the study aims to determine if the antibody can prevent those who get COVID-19 from getting so sick they need to be hospitalized – and if it can, “well, we really need that right now,” Haljan said.

“We’re in the third wave,” Haljan said of the pandemic. “This is the worst it’s been (in the SMH intensive care unit) yet. We’re working about as hard as we can right now in the ICU.

“This third wave has been a real kick in the pants.”

Researchers also want to learn if bamlanivimab can reduce the long-term effects of the illness.

Its use for COVID-19 treatment in high-risk patients has interim approval from Health Canada. The drug is designed to block the COVID-19 virus from attaching to and entering cells, thus potentially preventing the illness from worsening in newly diagnosed patients.

“Once you get an infection, it’s too late for a vaccine to work,” Haljan said. “What we want to do is provide those antibodies (that a vaccine typically triggers a body to produce) early in the disease, to give the immune system a head start.”

Recruiting for the study opened in March to residents of Surrey, White Rock and Delta. It then expanded to include patients living in Burnaby, Langley, Maple Ridge and Pitt Meadows.

Haljan said participants must begin the therapy within three days of a positive COVID-19 test, or within 10 days of their first symptoms.

Eligible participants are those 65 and older, or between 18 and 64 years old who have tested positive for COVID-19 and have at least one illness or condition that puts them at risk of being hospitalized for COVID-19 infection.

Haljan hopes to recruit up to 20 patients per day over the next two weeks, in order to complete the study by May 9.

Currently, the medication is being delivered at an infusion clinic set up at Peace Arch Hospital, but Haljan said the hope is to establish more clinics this week, particularly in the Fraser East area.

He emphasized that while the medication only has interim approval, it is “very safe,” and, it has been found to “retain activity” against the U.K variant of COVID-19; the most prevalent variant in Canada.

READ MORE: U.K variant of coronavirus detected at seven schools in Surrey, Delta

The study, he noted, “is asking questions nobody else in the world is asking right now about this drug.”

To sign up or for more information, visit www.bepicstudy.ca



tholmes@peacearchnews.com
Like us on Facebook and follow us on Twitter

CoronavirusSurreywhite rock

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Langley’s Madison Sweeney a 5’8” forward who began her career playing for Walnut Grove Secondary, has signed with the University of the Fraser Valley (UFV) Cascades women’s soccer team. (Special to Langley Advance Times)
Langley’s Madison Sweeney signs with UFV Cascades soccer team

UFV ‘checks all the boxes’ for former Walnut Grove player

Langley is home to a wide range of outstanding athletes, ranging from cycling champion Svein Tuft to MMA fighter Tristan Connelly and figure skating legend Karen Magnussen (files)
Making a list of Langley’s outstanding athletes

Website organizer is looking for suggestions

On hand for the presentation of a cheque to the Langley Food Bank was Jim Calamunce, executive director of the food bank (L), Langley City councillor Rudy Storteboom (centre) and Mike Partridge, manager of the South Langley IGA. (R) (Special to Langley Advance Times)
Shoppers at Langley IGA stores donate $10K to food bank

Customers showed ‘incredible generosity’ says store spokesperson

When they heard about the vandalism at the outdoor school in Williams Park, students at R.E.Mountain school created a replacement for the outdoor mud kitchen. Because of continuing thefts and vandalism at the outdoor school, the play kitchen is being stored indoors after hours. (Special to Langley Advance Times)
Langley students craft a new ‘mud kitchen’ to replace one vandalized at outdoor school

It isn’t being left outdoor after hours due to continuing problems with vandalism and theft

A bullet hole is seen in the windshield of an RCMP vehicle approximately 4 km from Vancouver International Airport after a one person was killed during a shooting outside the international departures terminal at the airport, in Richmond, B.C., Sunday, May 9, 2021. THE CANADIAN PRESS/Darryl Dyck
Homicide team IDs man in fatal YVR shooting as police grapple with spate of gang violence

Man, 20, charged in separate fatal shooting Burnaby over the weekend

The Canadian Forces Snowbirds are in the Comox Valley for their annual spring training. Photo by Erin Haluschak
Suspected bird strike on Snowbirds plane during training in B.C.

Pilot followed protocols and landed the aircraft on the ground without any problems

BCIT. (Wikimedia Commons)
BCIT apologizes after employee’s ‘offensive and hurtful’ email leaked to Métis Nation

BCIT says employee’s conduct has been investigated and addressed

Cannabis bought in British Columbia (Ashley Wadhwani/Black Press Media)
Is it time to start thinking about greener ways to package cannabis?

Packaging suppliers are still figuring eco-friendly and affordable packaging options that fit the mandates of Cannabis Regulations

An adult male yellow-breasted chat is shown in this undatd photograph on lands protected in collaboration between the En’owkin Centre and Penticton Indian Band with support through ECCC. The rescue from near extinction for a little yellow bird hinges on the wild rose in British Columbia’s Okanagan Valley, a researcher says. THE CANADIAN PRESS/HO, A. Michael Bezener/ En’owkin Centre 2020 *MANDATORY CREDIT*
Rare yellow birds need wild roses to survive in British Columbia: researcher

The importance of local wild roses emerged over a nearly 20-year experiment

RCMP officers search around rows of luggage carts as screens block off an area of the sidewalk after a shooting outside the international departures terminal at Vancouver International Airport, in Richmond, B.C., Sunday, May 9, 2021. THE CANADIAN PRESS/Darryl Dyck
Police say gang conflict in Metro Vancouver may be behind shooting death at airport

Police said this generation of gangsters is taking things to new level and have no regard for community safety

RCMP are looking for information on an alleged shooting attempt near an elementary school in Smithers March 10. (Phil McLachlan/Capital News/Stock)
UPDATE: Man killed in brazen daylight shooting at Vancouver airport

Details about the police incident are still unknown

Pieces of nephrite jade are shown at a mine site in northwestern B.C. in July 2019. THE CANADIAN PRESS/HO-Tahltan Central Government MANDATORY CREDIT
Indigenous nation opposes jade mining in northwestern B.C.

B.C.’s Mines Act requires operators to prepare a plan to protect cultural heritage resources

Most Read